Cannabis or weed possesses cannabinoids that elicit euphoria, while magic mushrooms or shrooms have alkaloids that allow psychedelic experiences.
Both substances are often consumed separately, but other users like to combine them to get a unique experience. However, mixing the two isn’t simple, and there are effects as a result that you should know about.
Keep reading to know these effects and the measures to observe during and after mixing the weed and shrooms.
To understand the compatibility between cannabis and mushrooms regarding effects, you must understand their differences.
Cannabis
As a member of the plant kingdom, cannabis creates its own food through photosynthesis. Several cannabinoids from this plant are responsible for the therapeutic and recreational effects weed is known for.
Two of its primary cannabinoids are Delta 9 tetrahydrocannabinol and CBD. The former gives feelings of getting high, while the latter has been studied for its medicinal properties.
Consuming cannabis, whether smoked or sublingually administered, offers the following experience:
Effects and onset period may vary according to the cannabis strain, dose, method of consumption, and person’s tolerance.
Mushrooms
Psilocybin mushrooms, magic mushrooms, or simply shrooms are naturally occurring plant-like fungi that give hallucinogenic effects.
Its key ingredient is the psychoactive psilocybin, which converts into the body as psilocin.
As a strong psychedelic, shrooms can alter your sense of time, perception, and emotion. Higher dosages could make the person hallucinate or see or hear things that don’t exist.
Here are some of the physical effects of shrooms but not limited to:
Aside from how each set of effects differs, weed and shrooms also have several distinctive characteristics regarding consumption and mechanism of action.
Let’s compare both substances’ consumption methods and mechanism of action in the human body.
Cannabis has four consumption methods – inhalation, digestion, sublingual administration, and topical.
Smoking weed is one of the most popular consumption of cannabis. It’s simple, and the onset of effects is fast (under 10-30 minutes).
Cannabis edibles are sweet gummies or candies you can chew. They’re renowned for the lengthy duration of effects but slow onset.
The sublingual administration (the absorption of cannabis oil under the tongue) of cannabis oil sends cannabinoids directly to the bloodstream. It has a rapid onset without the byproducts often obtained from smoking cannabis.
Lastly, cannabis can also be applied on the skin in the form of creams, serums, lotions, etc. This method rarely gives a feeling of high as only small amounts of compound reach the bloodstream.
In contrast, shrooms are eaten fresh or infused in food and beverages.
The “lemon tek” method, which involves soaking dried magic mushrooms into a lemon tea or juice, is especially popular among shroom consumers.
Smoking shrooms is less popular as burning the fungi lessens the potency.
Weed and shroom differ in sets of effects because their metabolites target different brain pathways.
Knowing how each substance works in the body gives a clue about the potential synergy or lack of compatibility between cannabis and magic mushrooms.
Look at the similarities and differences in the mechanism of action between the two:
If you are to follow the journey of cannabis’s THC metabolite in the body through the inhalation method, here’s how it goes:
As the THC molecules pass through the blood-brain barrier, THC metabolites will enter the brain, and several things happen simultaneously. THC will latch in receptors that will release effects like euphoria.
On the other hand, when psilocybin (Shroom’s psychedelic compound) enters the brain, the metabolites bind to serotonin receptors.
This binding slightly interferes with cognitive processing, giving the impression of mind-altering effects.
Here’s a comparison table summarizing each weed and shroom’s aspects of usage.
| Substance | Effects | Consumption Methods | Mechanism of Action |
| Cannabis |
|
| Cannabinoids enter the bloodstream and bind with the endocannabinoid receptors. |
| Shrooms |
|
| Psilocybin metabolites bind to serotonin receptors. |
Mixing weed and shrooms produces various effects that mainly depend on the dose and tolerance of the individual.
Some people would feel a heightened sensory experience. For example, the colors of flowers would be unusually brighter, or the landscape would look more vivid.
Others report feeling at ease, introspective, or sometimes wanting to discuss philosophical ideas such as existentialism.
Generally, mixing weed together with magic mushrooms simply enhances the psychedelic experience taken from shrooms and vice versa. The effects may suit some regular users but might be overwhelming for newbies.
Other users report combining cannabis with psilocybin mushrooms enhances the medicinal benefits of both substances.
For example, weed offsets the intense psychedelic effects of mushrooms by supporting relief from anxiety and improving mood.
Additionally, a study by Joanna Kuc et al. shows that combining cannabis with magic mushrooms supports deeper mystical experiences that may evoke unity, positivity, and sacredness.
While some consumers are fans of the combinatory effects between cannabis and mushrooms, it’s important to be aware of the risks involved to plan accordingly.
Although this seldom happens, you could sometimes experience a “bad trip” from smoking cannabis while on shrooms. Bad trips increase the potential for adverse effects such as palpitations.
Both weed and shrooms have some similarities in affecting the human brain. For example, both can effectively alter one’s state of mind and other cognitive abilities.
For this reason, many hope combining the two would create synergistic effects – enhancing one another’s beneficial effects.
While clinical trials are yet to be outlined on the compatibility between cannabis and magic mushrooms, anecdotal reports give some glimpse into the safety and efficacy of these substances when taken together.
For example, some users report that cannabis products with high CBD content reduce the uncomfortable side effects of shrooms. Additionally, high-THC cannabis products increase the hallucinogenic effects of magic mushrooms.
So yes, you can mix weed with shrooms, but this has to be controlled and planned accordingly since the effects vary and are unpredictable.
Before you try to handle a bad reaction, determine if it’s indeed an adverse one. Most often, a bad reaction would mean worsening anxiety and paranoia.
Once confirmed that what you’re experiencing is a bad reaction, most of the time, the presence of a sober friend is enough to find relief from these feelings.
Your friend or “trip-sitter” should be able to gently reassure that your reaction is due to the layers of effects between weed and shrooms. Most importantly, he or she should be able to reason with you that these feelings are “temporary” and should pass.
Sometimes, removing yourself from an environment that causes trippy sensations helps. Hence, try to safely get out of bars, a place full of mirrors, or any space where your senses could get overloaded.
Eating snacks and sipping water helps to lessen the trip’s intensity, too.
Believe it or not, you can tweak the effects of cannabis and mushrooms. Do this by concocting suitable cannabis strains to combine with magic mushrooms.
If you want a combination that will give a significant mood boost or energy, try mixing cannabis strains rich in THC with magic mushrooms.
Beginners are recommended to start with Indica strains with a higher CBD ratio. It’s a great addition to magic mushrooms for balancing its psychedelic effects and a lesser chance for bad trips to happen.
This section shows how pro mixers combine their magic mushrooms with cannabis.
First, you need to treat cannabis as a “supplementary” ingredient to the mix, while shrooms should be the majority ratio. So, dose your shrooms normally and add the least amount of cannabis.
Here are some quick tips to note:
Tip 1: Choose a cannabis strain with high levels of CBD and lesser THC ratio (especially recommended for beginners).
Tip 2: Use the method of smoking consumption you’re familiar with. Others like the simplicity of joints, while others like the large vapors drawn from bongs.
Tip 3: Select a non-working day and an environment with minimal stressors that you would typically find relaxing.
It’s also a good idea to walk outside occasionally, but don’t drive or operate any type of machinery.
Tip 4: Choose a friend that would serve as your trip sitter. Keep in mind that they should be sober throughout the process.
Tip 5: Keep your essentials within reach, such as water bottles.
Used together, mushrooms and cannabis enhance each other’s effects. Some people may find this unique experience as something they could enjoy. For others, it would take time to acclimate to the experience.
Proper knowledge is your best bet for a safe and enjoyable experience from mixing weed with shrooms. Thus, educate yourself by reading credible guides before embarking on the weed and shroom mixing session.
Can you smoke weed and do shrooms?
Yes. Smoking is the main way of getting the combinatory effects of cannabis and shrooms.
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